ERIC B. LARSON, M.D., M.P.H.; BURTON V. REIFLER, M.D., M.P.H.; HARVEY J. FEATHERSTONE, M.D., M.P.H.; DALLAS R. ENGLISH, Ph.D.
We prospectively studied the evaluation of dementia in 107 unselected outpatients; 83 had so-called "irreversible" dementias, including 74 who had an Alzheimer-type dementia. Fifteen patients had potentially reversible dementias, of which hypothyroidism and drug toxicity were the commonest causes. Distinguishing features of reversible dementia were shorter duration, use of more prescription drugs, and less severe dementia. Almost half of the patients had other previously unrecognized treatable medical diseases. Most diagnoses were made from patient history and physical and mental status examination. Patients with reversible dementia improved but rarely reverted to normal. Objective improvement occurred in 25 patients after treating unrecognized
LARSON EB, REIFLER BV, FEATHERSTONE HJ, et al. Dementia in Elderly Outpatients: A Prospective Study. Ann Intern Med. 1984;100:417–423. doi: 10.7326/0003-4819-100-3-417
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Published: Ann Intern Med. 1984;100(3):417-423.
Dementia, Geriatric Medicine, Neurology.
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