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To the editor: Weinreich and coworkers' (1) long-term follow-up with serial echocardiography of patients at risk for left ventricular mural thrombi after acute myocardial infarction is probably the first study to prove the important role of long-term oral anticoagulation in the prevention of systemic emboli.
The authors state that a dose of warfarin was administered to maintain the prothrombin time between 1.5 to 2 times the control value, but no information is given about the modification of the prothrombin time test nor about the tissue type and brand of the thromboplastin used. If Quick's test was used together with one
LOELIGER E. Oral Anticoagulation to Prevent Systemic Emboli. Ann Intern Med. ;101:570–571. doi: 10.7326/0003-4819-101-4-570_2
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Published: Ann Intern Med. 1984;101(4):570-571.
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