CORWIN Q. EDWARDS, M.D.
This content is PDF only. Please click on the PDF icon to access.
Hereditary hemochromatosis is inherited as an autosomal recessive trait linked to the histocompatibility locus on the short arm of chromosome six (1-4). Homozygosity for hemochromatosis among whites is probably common, with an estimated gene frequency of 0.05 to 0.088, corresponding to a heterozygote frequency of 10% to 16% and a disease frequency of 3 to 8 per 1000 population (5-8). Because many persons may have undiagnosed hereditary hemochromatosis, there is need for a simple, inexpensive test to identify young hemochromatosis homozygotes. Because a defective gene product has not been identified, alternates (such as blood tests of iron stores) have to
EDWARDS CQ. Early Detection of Hereditary Hemochromatosis. Ann Intern Med. 1984;101:707–708. doi: 10.7326/0003-4819-101-5-707
Download citation file:
Published: Ann Intern Med. 1984;101(5):707-708.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use