CLADD E. STEVENS, M.D.; RICHARD D. AACH, M.D.; F. BLAINE HOLLINGER, M.D.; JAMES W. MOSLEY, M.D.; WOLF SZMUNESS, M.D.; RICHARD KAHN, Ph.D.; JOCHEWED WERCH, M.D.; VIRGINIA EDWARDS, B.S.
Patients who received transfusions and nontransfused control patients were followed to assess the incidence and cause of post-transfusion hepatitis and to identify donor factors that might relate to risk of hepatitis. We evaluated as risk factors in donors the presence of antibody to hepatitis B virus compared with elevated alanine aminotransferase (ALT) level. Units of blood that were positive for antibody to hepatitis B core antigen (anti-HBc) were associated with a twofold to threefold greater risk of non-A, non-B hepatitis in the recipients than were units without anti-HBc. In the absence of specific serologic tests for non-A, non-B agents, screening
STEVENS CE, AACH RD, HOLLINGER FB, et al. Hepatitis B Virus Antibody in Blood Donors and the Occurrence of Non-A, Non-B Hepatitis in Transfusion Recipients: An Analysis of the Transfusion-Transmitted Viruses Study. Ann Intern Med. 1984;101:733–738. doi: 10.7326/0003-4819-101-6-733
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Published: Ann Intern Med. 1984;101(6):733-738.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease.
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