W. DOUGLAS WEAVER, M.D.; LEONARD A. COBB, M.D.; DEBBIE DENNIS, R.N.; ROBERTA RAY, M.S.; ALFRED P. HALLSTROM, Ph.D.; MICHAEL K. COPASS, M.D.
The amplitude of ventricular fibrillation found initially in 394 patients was compared to clinical and logistical findings at the time of cardiac arrest. Peak-to-peak amplitude averaged 0.55±0.25 mV; a very low amplitude (0.2 mV or less) or "fine" fibrillation was present in 66 patients (17%). The amplitude was not found to be related to clinical histories, but depended on the length of the period from collapse until start of basic life support (p=0.004) and the delay until assessment by paramedics (p=0.001). Survival rates were strongly associated with amplitude: only 4 patients (6%) with fine ventricular fibrillation survived, compared to 117 or 328 patients (36%) in whom the initial amplitude was higher (p < 0. 001). Patient outcome related to amplitude even after adjusting for clinical history and logistical delays (p < 0.005). We conclude that fine ventricular fibrillation is in part the result of delay in initiation of treatment, and that fibrillation amplitude is a powerful indicator of outcome after cardiac arrest.
WEAVER WD, COBB LA, DENNIS D, et al. Amplitude of Ventricular Fibrillation Waveform and Outcome After Cardiac Arrest. Ann Intern Med. 1985;102:53–55. doi: https://doi.org/10.7326/0003-4819-102-1-53
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Published: Ann Intern Med. 1985;102(1):53-55.
Cardiology, Emergency Medicine, Rhythm Disorders and Devices.
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