JORDAN B. GLASER, M.D.; LINDA MORTON-KUTE, M.D.; SCOTT R. BERGER, M.D.; JOHN WEBER, P.A.; FREDERICK P. SIEGAL, M.D.; CARLOS LOPEZ, Ph.D.; WILLIAM ROBBINS, M.D.; SHELDON H. LANDESMAN, M.D.
Seven Haitian and one white patient with the acquired immunodeficiency syndrome and Salmonella typhimurium bacteremia were identified over a 28-month period. In three patients bacteremia developed concurrently with an opportunistic infection associated with the acquired immunodeficiency syndrome. The remaining five patients had their initial episodes of bacteremia 3 to 11 months before the diagnosis of the acquired immunodeficiency syndrome. These five patients had signs suggestive of the syndrome, plus evidence of disordered cellular immune function (lymphopenia, anergy, decreased T-helper cells, decreased proliferative responses, and a deficiency in mononuclear-cell alpha interferon production). Salmonella typhimurium bacteremia in the appropriate clinical setting may be an opportunistic pathogen associated with the acquired immunodeficiency syndrome.
GLASER JB, MORTON-KUTE L, BERGER SR, et al. Recurrent Salmonella typhimurium Bacteremia Associated with the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1985;102:189–193. doi: 10.7326/0003-4819-102-2-189
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Published: Ann Intern Med. 1985;102(2):189-193.
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