DANIEL R. CUMMINGS
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To the editor: Moore and colleagues (1) found by univariate analysis that age did not correlate with the development of aminoglycoside nephrotoxicity. The age distribution of patients who developed nephrotoxicity was the same as the age distribution of those who did not (p = 0.53). Nevertheless, by multivariate discriminant analysis they found that age was a significant discriminant factor, and that it was the most important factor identified before aminoglycoside treatment was initiated. Is there an explanation for these contradictory results?
CUMMINGS DR. Aminoglycoside Nephrotoxicity and Age. Ann Intern Med. ;102:275. doi: 10.7326/0003-4819-102-2-275_2
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Published: Ann Intern Med. 1985;102(2):275.
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