DALE C. SNOVER, M.D.
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To the editor: In the article by Kotler and associates (1), I was interested in the conclusion regarding the histopathology of the rectal epithelium in their patients with enteropathy and the acquired immunodeficiency syndrome and the conclusion focal degeneration of crypt epithlial cells (apoptosis) was characteristic of this enteropathy and suggested a specific pathologic process. However, it is difficult to draw those conclusions from the material presented, because the finding of apoptotic bodies in rectal epthelium appears to be nonspecific and needs to be interpreted in its clinical context.
The authors noted that apoptotic bodies have been found in graft-versus-host
SNOVER DC. Rectal Epithelium in the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;102:278–279. doi: 10.7326/0003-4819-102-2-278_3
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Published: Ann Intern Med. 1985;102(2):278-279.
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