DENNIS K. LEDFORD, M.D.; MARK D. OVERMAN, M.D.; AMERICO GONZALVO, M.D.; ANN CALI, Ph.D.; STEPHEN W. MESTER, M.D.; RICHARD F. LOCKEY, M.D.
We report the first case of a patient with the acquired immunodeficiency syndrome with myositis secondary to a microsporidan infection. Microsporida are ubiquitous spore-forming protozoans that most commonly infect arthropods and fish but also can infect other invertebrates and vertebrates including mammals (1, 2).
A 20-year-old black man had had progressive generalized muscle weakness with contractures for 7 months and fever, generalized lymphadenopathy, and an 18-kg weight loss over the last 5 months. He admitted to having had one homosexual contact (passive oral-genital) 1 year before admission. His close friends, including a female sexual partner; his family; and the previous
LEDFORD DK, OVERMAN MD, GONZALVO A, CALI A, MESTER SW, LOCKEY RF. Microsporidiosis Myositis in a Patient with the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;102:628–630. doi: 10.7326/0003-4819-102-5-628
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Published: Ann Intern Med. 1985;102(5):628-630.
HIV, Infectious Disease.
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