MASSIMO FIORILLI; MAURIZIO CARBONARI; BEATRICE SCARPATI; GIUSEPPINA SCANO; CARLO GAETANO; FERNANDO AIUTI
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To the editor: Virologic and seroepidemologic evidence strongly suggests an association between human T-lymphotropic virus type III (HTLV-III) infection and the acquired immunodeficiency syndrome and its related complex (1, 2). The rapidly increasing prevalence of HTLV-III antibodies in populations at risk for the syndrome (3) argues for the spreading of a "new" virus. This hypothesis, however, must be confirmed by serologic evidence in patients with recent infection (that is, demonstration of antibodies of the IgM isotype), because to our knowledge all reported studies have pointed to the presence of HTLV-III serum antibodies of the IgG isotype.
We screened 426 serum
FIORILLI M, CARBONARI M, SCARPATI B, et al. Immunoglobulins in the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1985;102:862–863. doi: https://doi.org/10.7326/0003-4819-102-6-862_2
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Published: Ann Intern Med. 1985;102(6):862-863.
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