JAN M. AGOSTI, M.D.; KIRK D. MILLER, M.D.; MARGUERITE PAPPAIOANOU, D.V.M., Ph.D.; ELAINE C. JONG, M.D.
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To the editor: Because of its rapid activity, quinine dihydrochloride is the drug of choice for the intitial treatment of severe Plasmodium falciparum infections. In the United States this drug must be obtained from the Centers for Disease Control, resulting in delays of up to 12 hours in starting therapy. Prompt therapy of P. falciparum infections is essential in reducing the risk of death. Indeed, a study of cerebral malaria in Thailand has shown that patients who died received quinine later in their illness than those who survived (1). We report the case of a patient with cerebral malaria treated
AGOSTI JM, MILLER KD, PAPPAIOANOU M, JONG EC. Plasmodium falciparum Malaria and Intravenous Quinidine Gluconate. Ann Intern Med. ;103:307. doi: 10.7326/0003-4819-103-2-307_1
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Published: Ann Intern Med. 1985;103(2):307.
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