NICOLAOS C. TASSOPOULOS, M.D.; GEORGE J. PAPAEVANGELOU, M.D.; ANASTASIA ROUMELIOTOU-KARAYANNIS, M.D.; ROBERT H. PURCELL, M.D.
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To the editor: In the June issue, Davis and Hoofnagle (1) present three cases of reactivation of chronic type B hepatitis mimicking acute clinical hepatitis with hepatitis B surface antigen (HBsAg) positivity. They also imply that if the prevalence of the chronic carrier state were high, as in Greece (2), cases of severe reactivation of chronic type B hepatitis might account for an appreciable percentage of cases of suspected acute viral hepatitis.
From May 1981 to May 1983, we followed prospectively, for at least 6 months, 548 adults with acute HBsAg-positive hepatitis admitted to the Athens Hospital for Infectious Diseases.
TASSOPOULOS NC, PAPAEVANGELOU GJ, ROUMELIOTOU-KARAYANNIS A, et al. Reactivation of Chronic Hepatitis B as Acute Viral Hepatitis. Ann Intern Med. 1985;103:481. doi: 10.7326/0003-4819-103-3-481_1
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Published: Ann Intern Med. 1985;103(3):481.
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