Apheresis is a technique in which whole blood is temporarily removed from the body, and in which constituents are separated and selected constituents are removed before retransfusion. This separation can be accomplished by gravity or with specially developed centrifuges. The introduction of continuous- and intermittent-flow centrifuges in the 1960s increased interest in apheresis. In plasmapheresis, or plasma exchange, the commonest procedure, plasma is removed and replaced with another fluid: either human serum albumin, fresh frozen plasma, plasma protein fraction, normal saline, or lactated Ringer's solution. Lymphoplasmapheresis involves removal of mononuclear cells as well as plasma, followed by an infusion of
Apheresis in Chronic Inflammatory Demyelinating Polyneuropathy and in Renal Transplantation. Ann Intern Med. ;103:630–633. doi: 10.7326/0003-4819-103-4-630
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Published: Ann Intern Med. 1985;103(4):630-633.
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