GLEN D. PARK, Pharm.D.; REYNOLD SPECTOR, M.D.
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To the editor: Very convincing arguments have been made for basing therapeutic decisions on data derived from controlled clinical trials when possible (1). There are several examples of treatments that cause significant morbidity and mortality that initially were not subjected to careful scientific scrutiny but subsequently were found to have little or no beneficial effect. Even relatively benign treatments should not be used unless scientific evidence shows the treatment is effective or unless there is reason to believe that the likely benefits far outweigh the risks. Therefore, it is incumbent on the physician to use scientifically valid studies in making
PARK GD, SPECTOR R. Hypocitraturic Calcium-Oxalate Nephrolithiasis. Ann Intern Med. ;104:723–724. doi: 10.7326/0003-4819-104-5-723_2
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Published: Ann Intern Med. 1986;104(5):723-724.
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