L. A. HEALEY, M.D.
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To the editor: The relative infrequency of Reiter's syndrome in homosexual men is puzzling since the distribution of the HLA-B27 antigen is the same in this group as in the population at large and the frequency of chlamydial and shigella infections is apparently increased. The study by Melbye and colleagues (1) suggests a possible explanation: infection by the human T-lymphotropic virus type III may so alter the immunologic profile that these men do not respond to those infections by developing this reactive form of arthritis.
HEALEY LA. Reiter's Syndrome in Homosexual Men. Ann Intern Med. ;105:145. doi: 10.7326/0003-4819-105-1-145_1
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Published: Ann Intern Med. 1986;105(1):145.
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