KIM S. CULP, M.D.; VERONICA K. PIZIAK, M.D., Ph.D.
BOTH DIARRHEA and constipation have been reported in patients with thyrotoxicosis (1, 2). Although theories support disturbances in gastrointestinal motility as the basis for these symptoms, the responsible mechanisms have yet to be defined (2, 3). Steatorrhea has been reported in hyperthyroidism, and both hyperphagia and hypermotility are believed to play important roles in this form of steatorrhea (4, 5). To our knowledge, secretory diarrhea has not been reported as a gastrointestinal manifestation of thyrotoxicosis.
A 47-year-old woman had severe, watery diarrhea and weakness. She had been healthy until 2 months before admission when she had the insidious onset of
CULP KS, PIZIAK VK. Thyrotoxicosis Presenting with Secretory Diarrhea. Ann Intern Med. ;105:216–217. doi: 10.7326/0003-4819-105-2-216
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Published: Ann Intern Med. 1986;105(2):216-217.
Endocrine and Metabolism, Gastroenterology/Hepatology, Thyroid Disorders.
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