MARIA ALOIZOU, M.D.; STEVEN LOMASKY, M.D.; PHILIP D. LIEF, M.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: In the January issue, Bolan and colleagues (1) describe their analysis of the distribution of pneumococcal serotypes isolated from blood and cerebrospinal fluid of vaccinated and nonvaccinated patients. Although we agree that their data support the use of pneumococcal vaccine in select segments of the population, caution must be used, particularly with regard to meningitis prophylaxis. A reanalysis of the data presented in Table 1 using a fourfold chi-square table reveals a significant increase in the percentage of total cerebrospinal fluid isolates obtained from vaccinated as opposed to nonvaccinated patients: 24. 9% compared with 11.7% (chi-square =
ALOIZOU M, LOMASKY S, LIEF PD. Pneumococcal Vaccine Efficacy. Ann Intern Med. 1986;105:463–464. doi: 10.7326/0003-4819-105-3-463_2
Download citation file:
Published: Ann Intern Med. 1986;105(3):463-464.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use