M. HOYOS; J. B. SARRIÓN; T. PÉREZ-CASTELLANOS; M. L. MARTY; J. BERENGUER
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To the editor: In their recent article on transfusion-associated hepatitis, Koziol and coworkers (1) suggest the adoption of the test for antibody to the hepatitis B core antigen (anti-HBc) as a surrogate test for detection of the non-A, non-B virus carrier state.
In a prospective study we evaluated the incidence of transfusion-associated hepatitis in 112 consecutive patients having open-heart surgery who received 1254 blood units (negative for hepatitis B surface antigen and normal aminotransferase levels) obtained from volunteer donors. Hepatitis was diagnosed when aminotransferase levels exceeded 2.5 times the upper limit of normal in two consecutive samples obtained 15 days
HOYOS M, SARRIÓN JB, PÉREZ-CASTELLANOS T, et al. Markers for Non-A, Non-B Hepatitis. Ann Intern Med. 1986;105:467. doi: 10.7326/0003-4819-105-3-467_2
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Published: Ann Intern Med. 1986;105(3):467.
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