MIGUEL YEBRA, M.D.; JAVIER SEGOVIA, M.D.; LUIS MANZANO, M.D.; JUAN A. VARGAS, M.D.; LUIS BERNALDO DE QUIRÓS, M.D.; JORGE ALVAR, M.D.
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To the editor: The worldwide spread of infection with the human immunodeficiency virus (HIV) may modify the usual expression of regional endemic diseases. Conversely, those atypical forms may enlarge the spectrum of the acquired immunodeficiency syndrome (AIDS).
A 37-year-old Spanish homosexual man was hospitalized in October 1986 with leukopenia. His leukocyte count was 2.2 X 109/L, with 43% lymphocytes. The patient was seropositive to HIV, with a T4/T8 ratio of 0.17. A bone marrow biopsy showed no abnormalities.
In March 1987, the patient developed oroesophageal candidiasis and was found to have two purplish macules on his face. Biopsy of the
YEBRA M, SEGOVIA J, MANZANO L, et al. Disseminated-to-Skin Kala-azar and the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1988;108:490–491. doi: https://doi.org/10.7326/0003-4819-108-3-490_2
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Published: Ann Intern Med. 1988;108(3):490-491.
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