JOHN S. CHEESBROUGH; ALAN MURRAY
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To the editor: We congratulate Dr. DiNubile on his thoughtful article (1). His comments on the basis for current dogma dictating the use of antibiotics in such patients, particularly the scanty data on which it is founded, are apt. However, he may be extrapolating from centers where staff with adequate experience to detect the subtle signs of emerging infections are readily available to centers that may not be so fortunate. In such units, discontinuing antibiotics may be more hazardous and a rigid policy for introducing amphotericin B more appropriate. This potentially confounding variable is difficult to quantify and assess in
CHEESBROUGH JS, MURRAY A. Stopping Antibiotics in Neutropenic Patients. Ann Intern Med. ;108:908. doi: 10.7326/0003-4819-108-6-908_1
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Published: Ann Intern Med. 1988;108(6):908.
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