LOUIS BETTAN, M.D.; JEAN-JACQUES LEFRERE, M.D.; DIDIER LOISEAU, M.D.; DANIEL CATTAN, M.D.; JEAN GUGENHEIM, M.D.; DIDIER SAMUEL, M.D.; HENRI BISMUTH, M.D.
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To the editor: Central thrombocytopenia is uncommon in liver cirrhosis (1) and has not been reported, to our knowledge, in hepatocellular carcinoma. We report the case of a patient with cirrhosis and central thrombocytopenia who developed hepatocellular carcinoma. The interest of this case lies in the return to normal of the platelet count after liver transplantation.
A 46-year-old alcoholic man was admitted because of pain in the right hypochondriac region. The clinical examination showed hepatomegaly without splenomegaly or signs of portal hypertension. No ecchymosis or purpura was found. His total bilirubin level was 30 µmol/L; alkaline phosphatase and aminotransferase levels
BETTAN L, LEFRERE J, LOISEAU D, et al. Central Thrombocytopenia and Liver Disease. Ann Intern Med. 1987;106:170. doi: 10.7326/0003-4819-106-1-170_1
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Published: Ann Intern Med. 1987;106(1):170.
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