ALAN S. NIES, M.D.; JOSEPH GAL, Ph.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: We noted with interest the article and accompanying editorial regarding the implementation of SI units in American medical journals (1, 2). Although the arguments are reasonable for the use of these units to describe the concentration of endogenous substances, SI units make less sense when applied to drugs. As long as drugs are administered in mass units, concentrations of drugs in the blood should be in mass/L so that clinicians may use the pharmacokinetic parameters of apparent volume of distribution (VD) and clearance to calculate appropriate loading and maintenance schedules of drugs for their patients (3). The
NIES AS, GAL J. Implementation of SI Units. Ann Intern Med. 1987;106:642. doi: 10.7326/0003-4819-106-4-642_2
Download citation file:
Published: Ann Intern Med. 1987;106(4):642.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use