E. A. LOELIGER, M.D.
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To the editor: Duke and colleagues (1) present evidence that anticoagulation with heparin does not improve the short-term prognosis in patients with acute partial stable stroke. The authors gave no data, however, on the quality of treatment applied. We only know that heparin was given by intravenous infusion to maintain the activated partial thromboplastin time between 50 and 70 seconds. Such definition of treatment is grossly insufficient. Only with the knowledge of the brand of reagent used to effect changes in thromboplastin time, as well as knowledge of the methods used to read the time and of the percentage of
LOELIGER EA. Heparin in Acute Partial Stable Stroke. Ann Intern Med. ;106:781–782. doi: 10.7326/0003-4819-106-5-781
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Published: Ann Intern Med. 1987;106(5):781-782.
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