FRED R. HIRSCH, M.D.; KELL ØSTERLIND, M.D.; PAUL E. G. KRISTJANSEN, M.D.; HEINE H. HANSEN, M.D.
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To the editor: The question whether examination of bone marrow is necessary for patients with small cell lung cancer has recently been raised by Campling and associates (1) and has also been the subject of an editorial (2). Our previous articles about this issue were cited (3, 4), which prompts us to comment on the article by Campling and associates.
The authors conclude that the pretreatment bone marrow examination does not have any clinically significant prognostic implication. When comparing patients with extensive disease with and without bone marrow involvement the authors found p values of 0.036 (Wilcoxon-Gehan) 0.075 (log rank),
HIRSCH FR, ØSTERLIND K, KRISTJANSEN PEG, et al. Bone Marrow Examination in Small Cell Lung Cancer. Ann Intern Med. 1987;106:913. doi: 10.7326/0003-4819-106-6-913_1
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Published: Ann Intern Med. 1987;106(6):913.
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