ROSS R. BAILEY, M.D.; BARBARA A. PEDDIE, Ph.D.
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To the editor: We read with interest the article by Dr. Stamm and colleagues (1), which stated that a 2-week regimen of treatment with trimethoprim-sulfamethoxazole or ampicillin proved as efficacious as 6 weeks of treatment with either drug. The authors concluded that a 2-week course of treatment was sufficient for the treatment of acute pyelonephritis.
There is now impressive evidence that a single dose of an appropriate antimicrobial agent is sufficient for the management of patients with acute cystitis or covert bacteriuria (2). For the treatment of acute pyelonephritis we consider the recommended duration of treatment to be
BAILEY RR, PEDDIE BA. Treatment of Acute Urinary Tract Infection in Women. Ann Intern Med. ;107:430. doi: 10.7326/0003-4819-107-2-430_1
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Published: Ann Intern Med. 1987;107(3):430.
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