M. NOPPEN, M.D.; B. VELKENIERS, M.D.; R. DIERCKX, M.D.; M. BRUYLAND, M.D.; L. VANHAELST, M.D., PH.D.
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To the editor: Graves disease with ophthalmopathy was diagnosed in a 37-year-old woman. Treatment consisted of propranolol, 20 mg three times a day, propylthiouracil, 100 mg three times a day; and plasmapheresis (three sessions over a period of 5 days; total plasma exchange, 7.5 L). According to a study protocol in our institution, this was followed by cyclosporine (Sandimmune; Sandoz Pharmaceuticals, East Hanover, New Jersey) 10 mg/kg · body weight (500 mg/d). After 3 weeks, thyroid function tests had returned to normal values, and there was a marked improvement of the ophthalmopathy on physical examination, Hertel exophthalmometry, and orbital computed
NOPPEN M, VELKENIERS B, DIERCKX R, et al. Cyclosporine and Myopathy. Ann Intern Med. 1987;107:945–946. doi: 10.7326/0003-4819-107-6-945_3
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Published: Ann Intern Med. 1987;107(6):945-946.
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