Eldad S. Kisch, MD, PhD; Benno Fischel, MD; Michael Yaron, MD
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To the Editor: That the effect of nonsteroidal anti-inflammatory drugs on blood pressure remains a concern is reflected in the recent article by Radick and colleagues (1). We believe that the conflicting reports on this issue are probably due to nonhomogeneity of populations studied for plasma renin status.
In 1977 we presented data at the annual scientific meeting of the Israel Endocrine Society, showing that in two groups of patients, one with labile or borderline hypertension and the other with rheumatoid arthritis, blood pressure rose after administration of indomethacin therapy only in some patients who had initial low plasma renin
Kisch ES, Fischel B, Yaron M. Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Ann Intern Med. ;109:344. doi: 10.7326/0003-4819-109-4-344_1
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Published: Ann Intern Med. 1988;109(4):344.
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