Gary M. Levine, MD
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The use of an intragastric space-occupying device for treating obesity has been supported by circumstantial clinical evidence. First, the gastric bezoars that develop after stomach surgery have been associated with early satiety and weight loss (1). In addition, ingenious gastric stapling and gastroplasty procedures have been used to create tiny gastric pouches that severely limit meal size (2). Finally, in obese rats, gastric balloons have been shown to slow gastric emptying and reduce food intake (3).
These physiologic findings have led to the development of intragastric balloons designed to produce afferent stimulation of the satiety centers (4-6). Implicit in this
Levine GM. Intragastric Balloons: An Unfulfilled Promise. Ann Intern Med. 1988;109:354–356. doi: https://doi.org/10.7326/0003-4819-109-5-354
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Published: Ann Intern Med. 1988;109(5):354-356.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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