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It is not necessary to be an expert in statistics or epidemiology to understand and use the principles for good clinical research. That premise underlies this collection of discussions on topics ranging from the philosophical issues of inference in clinical research to the practical issues of estimating sample sizes, designing data collection and management, and writing competitive proposals. It is written for anyone engaged in clinical research (or who wishes to be) who wants a basic understanding of the scientific issues involved, as well as a practical guide for actually designing and implementing a research plan.
The writing is generally
Designing Clinical Research: An Epidemiologic Approach. Ann Intern Med. 1988;109:602. doi: 10.7326/0003-4819-109-7-602_3
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Published: Ann Intern Med. 1988;109(7):602.
DOI: 10.7326/0003-4819-109-7-602_3