Scott D. Holmberg, MD; C. Robert Horsburgh Jr., MD; Robert H. Byers, PhD; Charles A. Schable, MS; Alan R. Lifson, MD, MPH; George R. Seage III, MPH; Ellie E. Schoenbaum, MD
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To the Editor: The reversion of results from tests for antibodies to human immunodeficiency virus (HIV) from positive to negative has been occasionally reported in persons with the acquired immunodeficiency syndrome (AIDS) late in their illness. Four of one thousand (0.4%) healthy HIV-seropositive men in the Multicenter AIDS Cohort study have also been reported to have seroreverted (1).
We have followed large numbers of persons in three cohort studies of HIV infection and AIDS and have information on 2030 persons observed for 10 928 person-years (2-4). To evaluate the seroreversions in these persons, we examined results and retested the serum
Holmberg SD, Horsburgh CR, Byers RH, et al. Errors in Reporting Seropositivity for Infection with Human Immunodeficiency Virus (HIV). Ann Intern Med. 1988;109:679–680. doi: https://doi.org/10.7326/0003-4819-109-8-679_2
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Published: Ann Intern Med. 1988;109(8):679-680.
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