Ian Frank, MD; Harvey M. Friedman, MD
The importance of cytomegalovirus infection in the immunocompromised host is well documented. Cytomegalovirus is the commonest form of life-threatening opportunistic viral infection in patients with the acquired immunodeficiency syndrome (AIDS) (1). The incidence of infection after renal transplantation, determined by rise in antibody titer or virus isolation, is 71%, averaged over 15 studies (2). Approximately 30% of heart transplant patients develop clinical cytomegalovirus disease, although subclinical infection can be documented in almost all patients (3). Cytomegalovirus is the commonest infectious cause of death after allogeneic bone marrow transplantation, primarily because of cytomegalovirus pneumonia (4).
The clinical characteristics of cytomegalovirus pneumonia
Frank I, Friedman HM. Progress in the Treatment of Cytomegalovirus Pneumonia. Ann Intern Med. ;109:769–771. doi: 10.7326/0003-4819-109-10-769
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Published: Ann Intern Med. 1988;109(10):769-771.
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