A. Bassa Malondra, MD, PhD; M. Fiol Picornell, MD; J. Terrasa Pons, MD; J.J. Torres Rovira, MD; J. Buades Reines, MD, PhD
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To the editor: We are writing in response to the letter (1) on fibrolamellar hepatocellular carcinoma, in which Ruffin points out that the cases of this tumor reported since 1941 have all originated in the United States. We report two cases of this tumor diagnosed in patients treated at our hospital.
A 25-year-old man was hospitalized for epigastric discomfort; anorexia was present for 5 months. Physical examination showed a liver edge 12 cm below the right costal margin. The erythrocyte sedimentation rate was 135 mm/h; alkaline phosphatase, 100 U/L (normal, ≤ 40 U/L); and gamma-glutamyltransferase, 89 IU/L (normal, ≤ 30
Malondra AB, Picornell MF, Pons JT, et al. European Cases of Fibrolamellar Hepatocellular Carcinoma. Ann Intern Med. 1989;110:324. doi: 10.7326/0003-4819-110-4-324
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Published: Ann Intern Med. 1989;110(4):324.
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