David M. Parenti, MD; Patience White, MD; Julie A. Matsumoto, MD
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To the Editor: Alexander and colleagues (1) recently described cerebral lesions visualized by magnetic resonance (MR) imaging in patients with the Sjögren syndrome. We caution against assuming that all MR abnormalities in cerebral white matter are due to an underlying collagen vascular disease. We report a case of the Sjögren syndrome and progressive multifocal leukoencephalopathy in an 18-year-old patient who had white matter lesions on an MR scan. These lesions were similar in appearance to some of those described by Alexander and colleagues.
A computed tomographic (CT) scan done without use of an intravenous contrast agent showed generalized atrophy and
Parenti DM, White P, Matsumoto JA. Magnetic Resonance Scanning in the Sjögren Syndrome. Ann Intern Med. ;110:408–409. doi: 10.7326/0003-4819-110-5-408_2
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Published: Ann Intern Med. 1989;110(5):408-409.
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