Alan G. Barbour, MD
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Lyme disease, or, as it is increasingly called, Lyme borreliosis, is currently the commonest arthropodborne infection in the United States and Europe (1, 2). It also appears to be a frequent zoonotic disease in the Soviet Union (3). The etiologic agent, Borrelia burgdorferi, is a spirochete that is transmitted from animal to animal by hard-bodied ticks of the genus Ixodes (4). For humans, who are inadvertent hosts for the ticks, Lyme borreliosis may be brief and inconsequential or chronic and disabling (5-7). Major manifestations in the skin, joints, or nervous system of some patients can evolve over years. The inflammation
Barbour AG. The Diagnosis of Lyme Disease: Rewards and Perils. Ann Intern Med. 1989;110:501–502. doi: https://doi.org/10.7326/0003-4819-110-7-501
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Published: Ann Intern Med. 1989;110(7):501-502.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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