Carolyn R. O'Connor, MD; Thomas M. O'Dorisio, MD
This content is PDF only. Please click on the PDF icon to access.
To the Editor: Initially, somatostatin analogues were reported to be effective in treating secretory diarrhea that occurs in Werner-Morrison syndrome and carcinoid syndrome (1). Recently, a long-acting somatostatin analogue (SMS 201-995, octreotide acetate, Sandostatin) has been reported to be beneficial in treating other types of diarrhea (2, 3). We report the case of a patient with primary systemic amyloidosis who had diarrhea refractory to conventional treatment and whose symptoms were controlled with administration of SMS 201-995.
A 78-year-old man had a 6-month history of weight loss, anorexia, and six watery bowel movements daily. There was no family history of amyloidosis
O'Connor CR, O'Dorisio TM. Amyloidosis, Diarrhea, and a Somatostatin Analogue. Ann Intern Med. 1989;110:665–666. doi: https://doi.org/10.7326/0003-4819-110-8-665
Download citation file:
Published: Ann Intern Med. 1989;110(8):665-666.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use