Donald R. Varner Jr., MD, USAF; Mark W. Wolfe, MD, USAF; Geoffery A. Patrissi, MA
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To the Editor: We read with great interest the recent article by Achkar and Carey (1) and the accompanying editorial by Waye (2). The clinical significance of hyperplastic polyps in the left colon predicting pre-malignant-malignant histology on the right is certainly controversial with the finding by Zauber and colleagues (3) of a relative risk of only 1.2 (not significant). Achkar and Carey report an incidence of neoplastic polyps proximally in 29% of patients with solely hyperplastic polyps on sigmoidoscopic examination. The main concern raised by Waye is that this incidence corresponds very closely to a combined autopsy incidence of 30%
Varner DR, Wolfe MW, Patrissi GA. Colon Polyps in Asymptomatic Persons. Ann Intern Med. ;111:187. doi: 10.7326/0003-4819-111-2-187_1
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Published: Ann Intern Med. 1989;111(2):187.
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