David B. Edwards, MD
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To the Editor: Collagenous colitis is a relatively rare cause of watery diarrhea and abdominal pain and is characterized histologically by a thickened band of collagen beneath the colonic mucosa epithelium. I report a case of collagenous colitis associated with diffuse histiocytic lymphoma, which responded to sulfasalazine and steroid enemas, even as lymphoma progressed.
A 78-year-old woman with a 1-year history of diarrhea was admitted in February 1988 for a presumed stroke with mild aphasia. In the past year she had had four to five loose stools per day. At admission, cultures of the stool and examination for ova and
Edwards DB. Collagenous Colitis and Histiocytic Lymphoma. Ann Intern Med. ;111:260–261. doi: 10.7326/0003-4819-111-3-260
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Published: Ann Intern Med. 1989;111(3):260-261.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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