Charles M. Grossman, MD
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To the Editor: The recent article by Garber and colleagues (1) on serum cholesterol as a cardiac risk factor was very comprehensive and well documented. Is it fair, however, to add more weight to incorrect information in the literature? In both the abstract and the text, reference was made to the often expressed idea that "reduction of cholesterol levels lowers the incidence of and the mortality from coronary disease in asymptomatic, hypercholesterolemic, middle-aged men." The statement implies cause and effect. The report from the Lipid Research Clinics-Coronary Primary Prevention Trial (2) did show an association between lowering serum
Grossman CM. Cholesterol Screening and Coronary Artery Heart Disease. Ann Intern Med. ;111:341–342. doi: 10.7326/0003-4819-111-4-341
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Published: Ann Intern Med. 1989;111(4):341-342.
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