Robert L. Jayes, MD
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To the Editor: Dr. Lee and colleagues (1) are to be congratulated for showing the consequences of applying the published criteria for thrombolysis to emergency room patients with chest pain. However, the authors need to further explain the definition of chest pain used in the analyses. Although patients were stratified by the length of time since the onset of pain, the authors do not mention the duration of the episode of acute chest pain. A duration of 20 minutes was used as a criterion for thrombolytic therapy in one of the published trials (2) cited by the authors; however, the
Jayes RL. Emergency Room Patients, Chest Pain, and Thrombolysis. Ann Intern Med. ;111:685–686. doi: 10.7326/0003-4819-111-8-685
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Published: Ann Intern Med. 1989;111(8):685-686.
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