Marin H. Kollef, MD; Michael T. McCormack, MD; William E. Caras, MD; Vishnu V.B. Reddy, MD; David Bacon, MD
The fat overload syndrome is a rare complication of the intravenous administration of fat emulsion. It is characterized by sudden elevation of the serum triglyceride level associated with fever, hepatosplenomegaly, coagulopathy, and variable end-organ dysfunction (1-3). Specific successful therapy other than supportive care for the fat overload syndrome has not been described. We report the first successful use of plasma exchange in treating this condition.
A 39-year-old man was admitted to a community hospital for an exacerbation of his long-standing asthma. He was treated with intravenous theophylline, erythromycin, and nebulized metaproterenol. On the second hospital day, supplemental parenteral
Kollef MH, McCormack MT, Caras WE, Reddy VV, Bacon D. The Fat Overload Syndrome: Successful Treatment with Plasma Exchange. Ann Intern Med. ;112:545–546. doi: 10.7326/0003-4819-112-7-545
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Published: Ann Intern Med. 1990;112(7):545-546.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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