Stephanie D. Kafonek, MD; Peter O. Kwiterovich, MD
The major cause of death in elderly persons is atherosclerotic cardiovascular disease (1). This is not a phenomenon of normal human aging, but rather, a disease manifestation of extended cumulative exposure to conventional and unconventional risk factors. Most of the risk factors that predict coronary heart disease (CHD) in middle-aged persons also predict CHD in older persons (2).
The causal relationship between elevated total plasma cholesterol concentrations and CHD has been well established in middle-aged persons (3, 4). Analyses of data from prospective population studies have shown that this relationship also holds for persons aged 60 years and older (5-10).
Kafonek SD, Kwiterovich PO. Treatment of Hypercholesterolemia in the Elderly. Ann Intern Med. ;112:723–725. doi: 10.7326/0003-4819-112-10-723
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Published: Ann Intern Med. 1990;112(10):723-725.
Cardiology, Coronary Risk Factors, Dyslipidemia, Geriatric Medicine.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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