Pietro Martino, MD; Giovanna Meloni, MD; Antonio Cassone, MD
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To the Editor: The use of colony-stimulating factors associated with conventional antifungal therapy has recently been advocated to treat systemic fungal infections (1). We report the first case, to our knowledge, of catheter-related right-sided mural candidal endocarditis treated with fluconazole in association with recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF).
A 40-year-old man with acute nonlymphoid leukemia in first complete remission was hospitalized in July 1988 for autologous bone marrow transplantation. Six days after bone marrow infusion, the patient developed a fever and staphylococcal septicemia that subsided only after removal of the Hickman catheter. On day 14 after bone marrow infusion the
Martino P, Meloni G, Cassone A. Candidal Endocarditis and Treatment with Fluconazole and Granulocyte-Macrophage Colony-Stimulating Factor. Ann Intern Med. ;112:966–967. doi: 10.7326/0003-4819-112-12-966_2
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Published: Ann Intern Med. 1990;112(12):966-967.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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