Richard G. Farmer, MD; Linda Johnson White
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In our position paper on therapeutic substitution (1), we incorrectly cite cefazolin and cefotaxime as an example of therapeutic equivalents with the same pharmacokinetic and pharmacodynamic properties. The drugs are first- and third-generation cephalosporins. In reality, it is difficult to identify two drugs with exactly the same properties; the College's position paper deals with substitution of drugs with similar pharmacologic and therapeutic properties, as occurs in actual practice. We regret the error.
Farmer RG, White LJ. Correction: Therapeutic Substitution and Formulary Systems. Ann Intern Med. ;113:640. doi: 10.7326/0003-4819-113-8-640_2
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Published: Ann Intern Med. 1990;113(8):640.
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