Chantal Housset; Claire Hirschauer; Françoise Degos
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To the Editors: A high prevalence of anti-hepatitis C virus (HCV) antibodies detected by enzyme immunoassay (HCV-EIA, Ortho) (1) has been reported in patients with various liver diseases, particularly in those with auto-immune chronic liver disease (2). We used a recombinant-based immunoblot assay (RIBA, Chiron-Ortho) (3) to investigate the specificity of the HCV-EIA in 90 patients with histologically proven primary biliary cirrhosis. Liver histologic stages according to Scheuer (4) were 1-2, 3, and 4 in 25, 22, and 43 patients, respectively. Serum samples were stored at -20 °C until tested, for less than 2 months and for 2 to 48
Housset C, Hirschauer C, Degos F. False-Positive Anti-HCV in Biliary Cirrhosis. Ann Intern Med. ;114:252. doi: 10.7326/0003-4819-114-3-252_1
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Published: Ann Intern Med. 1991;114(3):252.
Biliary Disorders, Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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