James J. Rahal, MD
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To the Editors: The juxtaposition of two articles on Staphylococcus aureus in a recent issue (1, 2) sends a misleading message that methicillin-resistant S. aureus (MRSA) is a more virulent organism than methicillin-susceptible S. aureus (MSSA) and that it can be eradicated from hospital carriers by nasal application of mupirocin. Short-term eradication of staphylococcal carriage from healthy volunteers by mupirocin is not equivalent to long-term success in hospitalized patients. More importantly, Muder and colleagues (2) reported an increased number of infections among MRSA carriers compared with MSSA carriers without analyzing the two populations for three of the most important risk
Rahal JJ. Resistant Staphylococcal Infection. Ann Intern Med. ;114:911–912. doi: 10.7326/0003-4819-114-10-911
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Published: Ann Intern Med. 1991;114(10):911-912.
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