Ursula Kronawitter, MD; Johannes R. Bogner, MD; Frank D. Goebel, MD
This content is PDF only. Please click on the PDF icon to access.
To the Editors: Aerosolized pentamidine became available about 2 years ago, but the optimal dosage for prophylaxis of Pneumocystis carinii pneumonia has not yet been determined. We assessed the effects of a 300-mg dose of pentamidine inhaled every 2 weeks, adding 1 mL of salbutamol to the pentamidine to prevent bronchoconstriction.
Our study included 128 consecutive human immunodeficiency virus (HIV)-infected patients with the acquired immunodeficiency syndrome (AIDS) or a CD4 cell count of less than 250/µL. Within 8 weeks, 19 patients were withdrawn from study because of noncompliance and 2 patients died. Autopsy revealed P. carinii pneumonia in one patient.
Kronawitter U, Bogner JR, Goebel FD. Pentamidine Prophylaxis of Pneumocystis carinii Pneumonia. Ann Intern Med. 1991;115:497–498. doi: https://doi.org/10.7326/0003-4819-115-6-497_2
Download citation file:
Published: Ann Intern Med. 1991;115(6):497-498.
Infectious Disease, Pneumonia, Pulmonary/Critical Care.
Results provided by:
Copyright © 2020 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use