Skip Navigation
Menu
Brief Reports |15 October 1991

Disseminated Intravascular Coagulation after Factor IX Complex Resolved Using Purified Factor IX Concentrate

Terence Hadley, MD; Benjamin Djulbegovic, MD, PhD

FULL TEXT

Abstract

Patients with hemophilia B can be effectively treated with prothrombin complex concentrates (factor IX complex) that contain factors II, VII, IX, and X (1). A complication of therapy with factor IX complex is disseminated intravascular coagulation, attributed in part to activated factors in factor IX complex (2). We describe a patient with hemophilia B who developed disseminated intravascular coagulation while being treated with factor IX complex for a cerebellar hemorrhage. The patient's therapy was switched from factor IX complex to monoclonal antibody-purified factor IX (Mononine, Armour, Blue Bell, Pennsylvania), and the disseminated intravascular coagulation resolved.

FULL TEXT
PDF
Not Available
Citations
Citation

Hadley T, Djulbegovic B. Disseminated Intravascular Coagulation after Factor IX Complex Resolved Using Purified Factor IX Concentrate. Ann Intern Med. ;115:621–622. doi: 10.7326/0003-4819-115-8-621

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1991;115(8):621-622.

DOI: 10.7326/0003-4819-115-8-621

9 Citations

Related Articles
Review: For warfarin reversal, prothrombin complex concentrates reduce mortality compared with fresh frozen plasma
Annals of Internal Medicine; 165 (12): JC65
Rivaroxaban in a Patient With Disseminated Intravascular Coagulation Associated With an Aortic Aneurysm: A Case Report
Annals of Internal Medicine; 161 (2): 158-159
4F-PCC was noninferior to plasma in patients with acute major bleeding who needed urgent VKA reversal
Annals of Internal Medicine; 160 (8): JC6
No Hepatitis After Treatment with a Modified Factor IX Concentrate in Previously Untreated Hemophiliacs
Annals of Internal Medicine; 103 (2): 226-227
View MoreView Less

Journal Club
Review: For warfarin reversal, prothrombin complex concentrates reduce mortality compared with fresh frozen plasma
Annals of Internal Medicine; 165 (12): JC65
4F-PCC was noninferior to plasma in patients with acute major bleeding who needed urgent VKA reversal
Annals of Internal Medicine; 160 (8): JC6
View MoreView Less

Related Topics
Coagulopathies
Hematology/Oncology

Coagulopathies, Hematology/Oncology.

PubMed Articles
Infant identical triplets' presentation of human parechovirus Type 3.
IDCases 2019;15():e00494.
Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.
Front Immunol 2019;10():55.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×