Anders Jönsson, MD; Per Manhem, MD
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To the Editors: The use of the somatostatin analog octreotide is an established treatment in selected cases of acromegaly. Well-known side effects of octreotide are impaired glucose tolerance, development of gallstones, and diarrhea. We report diffuse loss of scalp hair as a possible new side effect, not previously described.
We have treated nine patients with acromegaly (7 women, 2 men, 32 to 75 years of age). Seven patients had a poor response to previous external irradiation (46 to 50 Gy) with octreotide for 2 to 21 months. Three patients developed gallstones (ultrasound), one developed diabetes mellitus, and all had diarrhea
Jönsson A, Manhem P. Octreotide and Loss of Scalp Hair. Ann Intern Med. 1991;115:913. doi: https://doi.org/10.7326/0003-4819-115-11-913_1
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Published: Ann Intern Med. 1991;115(11):913.
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