John B. Kostis, MD
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To the Editors: In their recent review, Anastos and colleagues concluded that clinical trials show no clear benefit of antihypertensive therapy for white women. Your readers may find it interesting that the recently completed Systolic Hypertension in the Elderly Program (SHEP), not published when the review was in press, showed a favorable effect in stroke incidence (the primary end point of SHEP) in this patient subset (1, 2). Although effects on white women were not included as a formal subgroup hypothesis of SHEP, this study included 2250 (47.5%) white women (3, 4). Forty-eight events occurred among the 1120 white women
Kostis JB. Treating Hypertension in Women. Ann Intern Med. ;116:92. doi: 10.7326/0003-4819-116-1-92_1
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Published: Ann Intern Med. 1992;116(1):92.
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