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Letters |15 May 1993

Cost-Effective Treatment of Candida Esophagitis

Daniel S. Berman, MD; Barry D. Wenglin, MD

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TO THE EDITOR:
Laine and colleagues' demonstration [1] that fluconazole is more effective than ketoconazole in treating candida esophagitis in patients with AIDS does not alter our position that ketoconazole is the primary therapy.
The investigators speak of endoscopic and clinical cure in the study patients. In treating human immunodeficiency virus (HIV)-infected patients over months and years, we have observed that it is the nature of candida pharyngitis and esophagitis to recur. We have also encountered the sequence of treatment failure with ketoconazole, followed by failure with fluconazoleeven high doses intravenously administeredand have had to use amphotericin B despite its...
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Berman DS, Wenglin BD. Cost-Effective Treatment of Candida Esophagitis. Ann Intern Med. 1993;118:824–825. doi: 10.7326/0003-4819-118-10-199305150-00013

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Published: Ann Intern Med. 1993;118(10):824-825.

DOI: 10.7326/0003-4819-118-10-199305150-00013

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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